Using Functional Magnetic Resonance Imaging to Detect Preserved Function in a Preterm Infant with Brain Injury

Charlotte Herzmann; Leire Zubiaurre-Elorza; Conor J Wild; Annika C Linke; Victor K Han; David S C Lee; Rhodri Cusack

doi:10.1016/j.jpeds.2017.06.063

Using Functional Magnetic Resonance Imaging to Detect Preserved Function in a Preterm Infant with Brain Injury

J Pediatr. 2017 Oct:189:213-217.e1. doi: 10.1016/j.jpeds.2017.06.063. Epub 2017 Jul 20.

Authors

Charlotte Herzmann¹, Leire Zubiaurre-Elorza², Conor J Wild², Annika C Linke², Victor K Han³, David S C Lee⁴, Rhodri Cusack⁵

Affiliations

¹ Brain and Mind Institute, Western University, London, Ontario, Canada. Electronic address: cherzmann@wustl.edu.
² Brain and Mind Institute, Western University, London, Ontario, Canada.
³ Children's Health Research Institute, London, Ontario, Canada.
⁴ Children's Health Research Institute, London, Ontario, Canada; Pediatrics, Western University, London, Ontario, Canada.
⁵ Brain and Mind Institute, Western University, London, Ontario, Canada; Children's Health Research Institute, London, Ontario, Canada.

PMID: 28735979
DOI: 10.1016/j.jpeds.2017.06.063

Abstract

We studied developmental plasticity using functional magnetic resonance imaging (fMRI) in a preterm infant with brain injury on structural MRI. fMRI showed preserved brain function and subsequent neurodevelopment was within the normal range. Multimodal neuroimaging including fMRI can improve understanding of neural plasticity after preterm birth and brain injury.

Keywords: developmental neuroimaging; developmental outcome; diffusion weighted imaging; functional connectivity MRI; neural networks; preterm infant.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Brain / pathology*
Brain Injuries / diagnosis*
Developmental Disabilities / diagnosis*
Humans
Infant, Newborn
Infant, Premature
Magnetic Resonance Imaging / methods*
Male