Regression of unusual optic disk neovascularization after adalimumab in a case of juvenile idiopathic arthritis-related uveitis

J AAPOS. 2017 Oct;21(5):412-414. doi: 10.1016/j.jaapos.2017.05.028. Epub 2017 Jul 13.

Abstract

We report the case of a 9-year-old girl with a severe and uncommon presentation of juvenile idiopathic arthritis-related posterior uveitis, with neovessels at the optic disk associated with peripheral vasculitis. After two failed bevacizumab intravitreal injections, uveitis responded to systemic adalimumab administration, with a complete and long-term remission of ocular inflammation.

Publication types

  • Case Reports

MeSH terms

  • Adalimumab / therapeutic use*
  • Antirheumatic Agents / therapeutic use*
  • Arthritis, Juvenile / drug therapy*
  • Child
  • Female
  • Fluorescein Angiography
  • Humans
  • Neovascularization, Pathologic / diagnosis
  • Neovascularization, Pathologic / drug therapy*
  • Optic Disk / blood supply*
  • Optic Disk / pathology
  • Uveitis, Posterior / drug therapy*
  • Visual Acuity

Substances

  • Antirheumatic Agents
  • Adalimumab