Partial Pulpotomy in Mature Permanent Teeth with Clinical Signs Indicative of Irreversible Pulpitis: A Randomized Clinical Trial

J Endod. 2017 Sep;43(9):1417-1421. doi: 10.1016/j.joen.2017.03.033. Epub 2017 Jun 30.

Abstract

Introduction: This study aimed to assess the outcome of partial pulpotomy using mineral trioxide aggregate (MTA) compared with calcium hydroxide (CH) in mature cariously exposed permanent molars.

Methods: Fifty permanent molar teeth with carious exposures in 50 patients >20 years old were included. Preoperative pulpal and periapical diagnosis was established based on a history of presenting pain, results of cold testing, and radiographic findings. After informed consent, the tooth was anesthetized, isolated via a dental dam, and disinfected with 5% sodium hypochlorite before caries excavation. Partial pulpotomy was performed by amputating 2 mm of the exposed pulp, hemostasis was achieved, and the tooth was randomly assigned for the placement of either white MTA (White ProRoot; Dentsply, Tulsa, OK) or CH (Dycal; Dentsply Caulk, Milford, DE) as the pulpotomy agent. Postoperative periapical radiographs were taken after placement of the permanent restoration. Clinical and radiographic evaluation was completed after 6 months and 1 and 2 years postoperatively. Statistical analysis was performed using the Fisher exact test.

Results: Clinical signs and symptoms suggestive of irreversible pulpitis were established in all teeth. Immediate failure occurred in 4 teeth. At 1 year, MTA showed a higher tendency toward success compared with the CH group, and the difference was statistically significant after 2 years (83% vs 55%, P = .052 at 1 year; 85% vs 43%, P = .006 at 2 years). Sex did not have a statistically significant effect on the outcome.

Conclusions: MTA partial pulpotomy sustained a good success rate over the 2-year follow-up in mature permanent teeth clinically diagnosed with irreversible pulpitis. More than half of the CH cases failed within 2 years.

Keywords: Calcium hydroxide; deep caries; mineral trioxide aggregate; partial pulpotomy; pulpitis.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aluminum Compounds / therapeutic use
  • Calcium Compounds / therapeutic use
  • Calcium Hydroxide / therapeutic use
  • Dental Cements / therapeutic use
  • Dentition, Permanent*
  • Drug Combinations
  • Female
  • Humans
  • Male
  • Middle Aged
  • Molar
  • Oxides / therapeutic use
  • Prospective Studies
  • Pulpitis / therapy*
  • Pulpotomy / methods*
  • Silicates / therapeutic use
  • Single-Blind Method
  • Young Adult

Substances

  • Aluminum Compounds
  • Calcium Compounds
  • Dental Cements
  • Drug Combinations
  • Oxides
  • Silicates
  • mineral trioxide aggregate
  • Calcium Hydroxide