BIlateral juxtapapillary retinal capillary haemangioma: Usefulness of aflibercept in the management of its complications

Arch Soc Esp Oftalmol. 2017 Oct;92(10):477-480. doi: 10.1016/j.oftal.2016.12.015. Epub 2017 Jun 23.
[Article in English, Spanish]

Abstract

Case report: A 45 year-old man with a history of adrenal phaeochromocytoma presented with a subretinal juxtapapillary haemorrhage on his left eye and a small asymptomatic vascular tumour in the contralateral eye. With the mentioned findings, the patient was diagnosed with bilateral retinal capillary haemangioma in the context of a von Hippel Lindau disease. Intravitreal aflibercept was prescribed, with a good outcome of the disease.

Discussion: Many treatments have been proposed for the management of juxtapapillary retinal capillary haemangioma with variable results. Intravitreal aflibercept can be a useful treatment with a good safety profile.

Keywords: Aflibercept; Enfermedad de von Hippel Lindau; Feocromocitoma; Hemangioma capilar retiniano; Hemorragia subretiniana yuxtapapilar; Phaeochromocytoma; Retinal capillary haemangioma; Subretinal juxtapapillary haemorrhage; Von Hippel Lindau disease.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Gland Neoplasms
  • Angiogenesis Inhibitors / administration & dosage
  • Angiogenesis Inhibitors / therapeutic use*
  • Fluorescein Angiography
  • Hemangioma, Capillary / complications*
  • Hemangioma, Capillary / diagnostic imaging
  • Humans
  • Intravitreal Injections
  • Male
  • Middle Aged
  • Neoplasms, Multiple Primary / diagnosis*
  • Neoplasms, Multiple Primary / diagnostic imaging
  • Neoplasms, Multiple Primary / genetics
  • Pheochromocytoma
  • Receptors, Vascular Endothelial Growth Factor / administration & dosage
  • Receptors, Vascular Endothelial Growth Factor / therapeutic use*
  • Recombinant Fusion Proteins / administration & dosage
  • Recombinant Fusion Proteins / therapeutic use*
  • Retinal Hemorrhage / drug therapy*
  • Retinal Hemorrhage / etiology
  • Retinal Neoplasms / complications*
  • Retinal Neoplasms / diagnosis
  • Retinal Neoplasms / diagnostic imaging
  • Retinal Neoplasms / genetics
  • Tomography, Optical Coherence
  • von Hippel-Lindau Disease / complications
  • von Hippel-Lindau Disease / diagnosis

Substances

  • Angiogenesis Inhibitors
  • Recombinant Fusion Proteins
  • aflibercept
  • Receptors, Vascular Endothelial Growth Factor