Red blood cell Gardos channel (KCNN4): the essential determinant of erythrocyte dehydration in hereditary xerocytosis

Haematologica. 2017 Oct;102(10):e415-e418. doi: 10.3324/haematol.2017.171389. Epub 2017 Jun 15.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Anemia, Hemolytic, Congenital / etiology*
  • Dehydration / etiology*
  • Erythrocytes / pathology*
  • Female
  • Gain of Function Mutation
  • Humans
  • Hydrops Fetalis / etiology*
  • Intermediate-Conductance Calcium-Activated Potassium Channels / genetics*
  • Ion Channels / genetics
  • Male
  • Mutation

Substances

  • Intermediate-Conductance Calcium-Activated Potassium Channels
  • Ion Channels
  • KCNN4 protein, human
  • PIEZO1 protein, human

Supplementary concepts

  • Xerocytosis, hereditary