Poncet's disease in human immunodeficiency virus: a case report

BMC Res Notes. 2017 Jun 12;10(1):203. doi: 10.1186/s13104-017-2525-9.

Abstract

Background: Poncet's disease is a rare reactive polyarthritis associated with active tuberculosis and no evidence of Mycobacterium tuberculosis in the affected joint.

Case presentation: We report a case of a 35 year old Human Immunodeficiency Virus positive Kenyan male of Kikuyu ethnicity from Kiambu County who presented to hospital with a 6 day history of bilateral knee pain and swelling, bilateral ankle pain with right ankle swelling. The patient reported 6 months history of cough and weight loss. Chest radiograph had features consistent with pulmonary tuberculosis and sputum smear was positive for acid fast bacilli. Analysis of fluid from knee effusion showed no evidence of tuberculosis. Resolution of joint swelling was seen after 3 weeks of tuberculosis chemotherapy suggesting that this was reactive arthritis following pulmonary tuberculosis in a patient infected with human immunodeficiency virus.

Conclusion: This case represents a rare manifestation of tuberculosis presenting as a reactive arthritis. There are very few cases of Poncet's disease reported in literature and the diagnosis of Poncet's disease in Human Immunodeficiency Virus/tuberculosis coinfected patient is extremely uncommon. This case report has been presented to raise awareness of this unusual tuberculosis complication and review its diagnosis and treatment.

Keywords: HIV; Reactive polyarthritis; Tuberculosis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antibiotics, Antitubercular / therapeutic use
  • Antiretroviral Therapy, Highly Active
  • Arthritis, Reactive / drug therapy
  • Arthritis, Reactive / etiology*
  • Ethambutol / therapeutic use
  • HIV Infections / complications*
  • HIV Infections / drug therapy
  • Humans
  • Isoniazid / therapeutic use
  • Male
  • Pyrazinamide / therapeutic use
  • Rifampin / therapeutic use
  • Tomography, X-Ray Computed
  • Tuberculosis, Pulmonary / complications*
  • Tuberculosis, Pulmonary / diagnostic imaging
  • Tuberculosis, Pulmonary / drug therapy

Substances

  • Antibiotics, Antitubercular
  • Pyrazinamide
  • Ethambutol
  • Isoniazid
  • Rifampin