Enhancement of endocytic uptake of HIV-1 virions into CD4-negative epithelial cells by HIV-1 gp41 via its interaction with POB1

Cell Mol Immunol. 2017 Jun;14(6):568-571. doi: 10.1038/cmi.2015.38. Epub 2015 May 25.

Authors

Yue Tan¹, Junyi Wang¹, Shan Su², Qian Wang², Shibo Jiang², Lu Lu², Ying-Hua Chen¹

Affiliations

¹ Laboratory of Immunology, School of Life Sciences, Beijing Key Laboratory for Protein Therapeutics, Protein Science Laboratory of the Ministry of Education, Tsinghua University, Beijing 100084, People's Republic of China.
² Key Laboratory of Medical Molecular Virology of Ministries of Education and Health, Shanghai Public Health Clinical Center and Shanghai Medical College, Fudan University, Shanghai 200433, People's Republic of China.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
CD4 Antigens / metabolism*
CHO Cells
Calcium-Binding Proteins
Cricetinae
Cricetulus
Endocytosis*
Epithelial Cells / metabolism*
HIV Envelope Protein gp41 / metabolism*
HIV-1 / metabolism*
Humans
Intracellular Signaling Peptides and Proteins / metabolism*
Protein Binding
Rats
Virion / metabolism*

Substances

CD4 Antigens
Calcium-Binding Proteins
HIV Envelope Protein gp41
Intracellular Signaling Peptides and Proteins
REPS2 protein, human