Frequency distribution of six cytokine gene polymorphisms in North- and South-Italy

Int J Immunogenet. 2017 Aug;44(4):158-163. doi: 10.1111/iji.12324. Epub 2017 May 26.

Abstract

Allelic and genotype frequencies of four cytokine genes were obtained from 738 subjects from North- and South-Italy. Populations were in Hardy-Weinberg equilibrium for all genes but significantly differed in the frequency of all SNPs and three haplotypes. In the MDS graph, they were plotted in separate positions close to Europeans and an Ivorian population, respectively.

Keywords: allele frequencies; cytokines; gene polymorphism; population study.

Publication types

  • Clinical Trial

MeSH terms

  • Cytokines / genetics*
  • Female
  • Gene Frequency*
  • Haplotypes*
  • Humans
  • Italy
  • Male
  • Middle Aged
  • Polymorphism, Single Nucleotide*

Substances

  • Cytokines