Blood pressure, heart rate, and double product in a pooled cohort: the Japan Arteriosclerosis Longitudinal Study

J Hypertens. 2017 Sep;35(9):1808-1815. doi: 10.1097/HJH.0000000000001399.

Abstract

Objective: To identify the characteristics of blood pressure (BP), heart rate (HR), and double product in a Japanese population sample.

Methods: We pooled individual records from 1999 to 2005 for 111 007 participants in 25 community-based cohorts and seven worksite-based cohorts. The data were analyzed to provide information on BP, HR, and double product according to age-sex groups and use of antihypertensive medication.

Results: Average BP was 130/77 mmHg among men and women combined. Among untreated individuals, SBP increased with age, whereas DBP reached a ceiling around the age of 60 years. The average SBP of treated participants was around 140 mmHg, irrespective of age, whereas DBP decreased linearly with age, and 56.4% of treated participants had a BP of 140/90 mmHg or over. HR did not differ across age groups or treatment status. The double product, also called the rate-pressure product, calculated by multiplying the SBP and the HR, increased with age among untreated individuals, whereas it first decreased and then increased with age among treated individuals.

Conclusion: Based on these collaborative data, insufficient BP control in Japan, where the average life expectancy is the longest in the world, was seen.

MeSH terms

  • Adult
  • Blood Pressure / physiology*
  • Female
  • Heart Rate / physiology*
  • Humans
  • Hypertension / epidemiology*
  • Japan / epidemiology
  • Longitudinal Studies
  • Male
  • Middle Aged