Association between muscle function and body composition, vitamin D status, and blood glucose in postmenopausal women with type 2 diabetes

Diabetes Metab Syndr. 2017 Dec:11 Suppl 2:S679-S684. doi: 10.1016/j.dsx.2017.04.025. Epub 2017 Apr 28.

Abstract

Aims: The aim of this study was to examine the association between muscle function, and body composition, vitamin D status, and blood glucose in post-menopausal women with type 2 diabetes (T2D).

Methods: Forty post-menopausal women (62.48±7.67years; 154.6±5.11cm; 73.93±15.43kg; 31.13±5.82 BMI kg/m2) with a diagnosis of T2D participated in this cross-sectional study. The patients performed fasting blood sample exams, anthropometrics assessments, body composition, and clinical exams. Subjects performed physical tests including handgrip, timed up and go, 30-s chair stand, arm curl, and sit-to-stand. The correlation between the parameters of physical tests, age, body composition, vitamin D, and blood glucose was assessed by Pearson correlation.

Results: The results showed there were significant correlations between blood glucose and relative strength (R=-0.398, p=0.011), arm curl test (R=-0.367 and p=0.020), and hip flexion (R=0.427, p=0.006).

Conclusions: These findings are important because they highlight the importance of resistance training in individuals with T2D and the relationship with a fat increase during a dicrease process. Furthermore, the concentration of serum glucose might be associated with decreases in muscle strength and muscle function in older adults. Thus, T2D patients should be involved with strength training to improve the strength and the muscle hypertrophy.

Keywords: Athletic performance; Cholecalciferol; Elderly women; Grip strength; Hyperglycemic; Metabolism.

MeSH terms

  • Blood Glucose / analysis*
  • Body Composition*
  • Cross-Sectional Studies
  • Diabetes Mellitus, Type 2 / physiopathology*
  • Female
  • Follow-Up Studies
  • Hand Strength / physiology*
  • Humans
  • Male
  • Middle Aged
  • Muscle Strength / physiology*
  • Postmenopause*
  • Prognosis
  • Vitamin D / blood*
  • Vitamins / blood

Substances

  • Blood Glucose
  • Vitamins
  • Vitamin D