Branchial arch anomalies: Recurrence, malignant degeneration and operative complications

Int J Pediatr Otorhinolaryngol. 2017 Jun:97:24-29. doi: 10.1016/j.ijporl.2017.03.014. Epub 2017 Mar 14.

Abstract

Objective: Branchial arch anomalies (BAA) represent one of the commonest pediatric neck masses, but large case series are lacking with none specifically examining risk of recurrence, surgical complications, and malignancy.

Study design: Retrospective study of patients with BAA at Mayo Clinic from 1/1/1976-7/29/2011.

Methods: Features studied include age, gender, location, BAA type, symptoms, recurrence, preoperative management, extent of surgery, pathology as well as presence of tracts. Associations with tracts, operative complications, and recurrence were evaluated.

Results: 421 subjects underwent BAA excision during the study period at our institution. Subjects with tracts were symptomatic earlier. Four cases (mean age 60.3 years) of malignancy were identified. Among the 358 (non-remenant) BAA patients with no previous excision, 3.6% recurred at a mean of 47.1 months following surgery. Patients who underwent incision and drainage prior to BAA excision were 3.4 times more likely to recur. 2% experienced complications. Age, BAA type, preoperative imaging and extent of surgery did not affect recurrence or complication rates.

Conclusion: Patients with history of preoperative incision and drainage should be followed closely for recurrence the first four years. Early BAA excision is not associated with higher complication rate. Extent of resection should be determined by gross margins of BAA. Malignant degeneration was not seen in children. Malignancies have been seen in older patients (over 45 years) diagnosed with BAA, and a thorough work-up is important for correct diagnosis.

Keywords: Branchial arch; Complications; Malignancy; Recurrence.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Branchial Region / abnormalities*
  • Branchial Region / surgery
  • Child
  • Child, Preschool
  • Craniofacial Abnormalities / epidemiology*
  • Craniofacial Abnormalities / surgery
  • Female
  • Humans
  • Infant
  • Male
  • Middle Aged
  • Pharyngeal Diseases / epidemiology*
  • Pharyngeal Diseases / surgery
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / etiology
  • Recurrence
  • Retrospective Studies
  • Survival Analysis
  • Young Adult

Supplementary concepts

  • Branchial Cleft Anomalies