Structure and gene cluster of a tyvelose-containing O-polysaccharide of an entomopathogenic bacterium Yersinia entomophaga MH96T related to Yersinia pseudotuberculosis

Carbohydr Res. 2017 Jun 5:445:93-97. doi: 10.1016/j.carres.2017.04.013. Epub 2017 Apr 15.

Abstract

An O-polysaccharide was isolated from the lipopolysaccharide of an entomopathogenic bacterium Yersinia entomophaga MH96T by mild acid hydrolysis and studied by 2D NMR spectroscopy. The following structure of the branched tetrasaccharide repeating unit of the polysaccharide was established: where Tyv indicates 3,6-dideoxy-d-arabino-hexose (tyvelose). The structure established is consistent with the gene content of the O-antigen gene cluster. The O-polysaccharide structure and gene cluster of Y. entomophaga are related to those of some Y. pseudotuberculosis serotypes.

Keywords: Bacterial polysaccharide structure; Lipopolysaccharide; O-antigen; O-specific polysaccharide; Tyvelose; Yersinia entomophaga; Yersinia pseudotuberculosis.

MeSH terms

  • Carbohydrate Sequence
  • Hexoses / chemistry*
  • Multigene Family*
  • O Antigens / chemistry*
  • Yersinia pseudotuberculosis / chemistry*
  • Yersinia pseudotuberculosis / genetics*

Substances

  • Hexoses
  • O Antigens
  • tyvelose