Hypoxic adaptation of leukemic cells infiltrating the CNS affords a therapeutic strategy targeting VEGFA

Affiliations

• ¹ Cancer Institute, University College London, London, United Kingdom.
• ² Department of Clinical Application, Center for iPS Cell Research and Application.
• ³ Department of Pediatrics, and.
• ⁴ Department of Life Science Frontiers, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan.
• ⁵ Department of Cellular Pathology, University College London, London, United Kingdom.
• ⁶ Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
• ⁷ Department of Hematology/Oncology, Saitama Children's Medical Center, Saitama, Japan.
• ⁸ Department of Plant Sciences, University of Oxford, Oxford, United Kingdom.
• ⁹ Human Health Sciences, Kyoto University, Kyoto, Japan.
• ¹⁰ Department of Pediatrics.
• ¹¹ Laboratory of DNA Information Analysis, Human Genome Center, Institute of Medical Science, and.
• ¹² Laboratory of Sequence Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
• ¹³ Department of Hematology and Oncology, Shizuoka Children's Hospital, Shizuoka, Japan; and.
• ¹⁴ Department of Advanced Diagnosis, Clinical Research Center, Nagoya Medical Center, Aichi, Japan.