[Evaluation of practices in the management of scabies in children]

Ann Dermatol Venereol. 2017 May;144(5):341-348. doi: 10.1016/j.annder.2016.12.008. Epub 2017 Apr 10.
[Article in French]

Abstract

Background: Scabies has been on the rise in France in recent years and has posed therapeutic problems, mainly due to the withdrawal of benzyl benzoate. The objective of this study was to describe prescribing practices for scabies in children.

Methods: A national survey was conducted by means of a standardized questionnaire covering various clinical situations of scabies and the drugs used preferentially according to age, which was sent out between December 2014 and March 2015 to members of the clinical research group of the French Society of Paediatric Dermatology.

Results: Of the 38 experts contacted, 20 replied. For a typical case of scabies, 55% of the experts initially prescribed oral ivermectin for children aged 6 years, 15% prescribed ivermectin in children aged 2 years, and 5% in infants aged 3 months. Ivermectin was more widely prescribed after failure of prior treatment or recurrence of scabies, on skin lesions or impetigo, if precarious, especially for profuse hyperkeratotic scabies. A total of 35% of the experts reported no prescribing restrictions with regard to patient age or weight. Discrepancies were observed concerning the mode of administration and the time between consecutive doses. Esdepallethrin remained the preferred local treatment among the experts (38% of all topical prescriptions) except in asthmatic children, while permethrin was the least-prescribed topical agent.

Discussion: This study confirms the heterogeneity of our practices. Formal expert recommendations are awaited, particularly concerning the use of ivermectin in infants.

Keywords: Esdepallethrin; Esdépalléthrine; Gale; Ivermectin; Ivermectine; Paediatrics; Pédiatrie; Scabies.

Publication types

  • Observational Study

MeSH terms

  • Administration, Cutaneous
  • Administration, Oral
  • Allethrins / administration & dosage
  • Antiparasitic Agents / therapeutic use*
  • Benzoates / administration & dosage
  • Child
  • Child, Preschool
  • Female
  • France
  • Humans
  • Infant
  • Insecticides / administration & dosage
  • Ivermectin / therapeutic use
  • Male
  • Permethrin / administration & dosage
  • Scabies / diagnosis
  • Scabies / drug therapy*
  • Surveys and Questionnaires
  • Treatment Outcome

Substances

  • Allethrins
  • Antiparasitic Agents
  • Benzoates
  • Insecticides
  • Permethrin
  • Ivermectin
  • benzyl benzoate