Evaluation of forensic genetic parameters of 12 STR loci in the Korean population using the InvestigatorⓇ HDplex kit

Ju Yeon Jung; Eun Hye Kim; Yu-Li Oh; Hyun-Chul Park; Jung Ho Hwang; Si-Keun Lim

doi:10.1007/s00414-017-1592-8

Evaluation of forensic genetic parameters of 12 STR loci in the Korean population using the Investigator^Ⓡ HDplex kit

Int J Legal Med. 2017 Sep;131(5):1247-1249. doi: 10.1007/s00414-017-1592-8. Epub 2017 Apr 11.

Authors

Ju Yeon Jung¹, Eun Hye Kim², Yu-Li Oh¹, Hyun-Chul Park¹, Jung Ho Hwang¹, Si-Keun Lim³

Affiliations

¹ Forensic DNA Division, National Forensic Service, Wonju, 26460, Republic of Korea.
² DNA Analysis Division, Seoul Institute, National Forensic Service, Seoul, 08636, Republic of Korea.
³ Forensic DNA Division, National Forensic Service, Wonju, 26460, Republic of Korea. neobios@korea.kr.

PMID: 28401303
DOI: 10.1007/s00414-017-1592-8

Abstract

We genotyped and calculated the forensic parameters of 10 non-CODIS loci and 2 CODIS loci of 990 Korean individuals using the Investigator^Ⓡ HDplex kit. No significant deviations from Hardy-Weinberg equilibrium (after Bonferroni correction for multiple testing) or genetic linkage disequilibrium were observed. The calculated matching probability and power of discrimination ranged from 0.0080 to 0.2014, and 0.7986 to 0.9920, respectively. We conclude that the markers of the kit are highly informative corroborative tools for forensic DNA analysis.

Keywords: Forensic genetic parameters; InvestigatorⓇ HDplex kit; Korean population.

MeSH terms

Asian People / genetics*
DNA Fingerprinting / instrumentation*
Gene Frequency
Genetics, Population*
Genotype
Humans
Microsatellite Repeats*
Polymerase Chain Reaction / instrumentation*
Republic of Korea