Impact of an integrated oral chemotherapy program on patient adherence

J Oncol Pharm Pract. 2018 Jul;24(5):332-336. doi: 10.1177/1078155217703792. Epub 2017 Apr 5.

Abstract

As the use of oral chemotherapy continues to rise, the issue of patient adherence is a concerning aspect of cancer treatment. In this concurrent prospective and retrospective study, we assessed oral chemotherapy adherence in patients receiving their prescriptions at an institutional specialty pharmacy, with an integrated oral chemotherapy program. The primary endpoint is medication possession ratio. Secondary endpoints include self-reported adherence comparing survey data before and after the introduction of the oral chemotherapy program to assess the impact of the comprehensive pharmacy services provided. Patients receiving their oral chemotherapy from the institutional specialty pharmacy have a mean medication possession ratio of 0.92, indicating excellent adherence rates. The oncology clinical pharmacist, in collaboration with the specialty pharmacy, has also decreased the rates of patient-reported non-adherence.

Keywords: Oral chemotherapy adherence; clinical pharmacy practitioner; specialty pharmacy.

MeSH terms

  • Administration, Oral
  • Aged
  • Antineoplastic Agents / administration & dosage*
  • Female
  • Humans
  • Male
  • Medication Adherence / statistics & numerical data*
  • Middle Aged
  • Pharmaceutical Services / organization & administration*
  • Pharmacists / organization & administration
  • Prospective Studies
  • Retrospective Studies

Substances

  • Antineoplastic Agents