A link closer to glioblastoma therapy

Sci Signal. 2017 Apr 4;10(473):eaan3515. doi: 10.1126/scisignal.aan3515.

Abstract

A next-generation mTOR inhibitor combines features of its predecessors to more potently and durably inhibit the growth of glioblastoma in mice.

Publication types

  • Comment

MeSH terms

  • Animals
  • Cell Line, Tumor
  • Disease Models, Animal
  • Glioblastoma*
  • Mechanistic Target of Rapamycin Complex 1
  • Mice
  • Protein Kinase Inhibitors
  • TOR Serine-Threonine Kinases / antagonists & inhibitors

Substances

  • Mechanistic Target of Rapamycin Complex 1
  • Protein Kinase Inhibitors
  • TOR Serine-Threonine Kinases