Impact of subsidies on cancer genetic testing uptake in Singapore

J Med Genet. 2017 Apr;54(4):254-259. doi: 10.1136/jmedgenet-2016-104302. Epub 2016 Oct 25.

Abstract

Purpose: Previous reports cite high costs of clinical cancer genetic testing as main barriers to patient's willingness to test. We report findings of a pilot study that evaluates how different subsidy schemes impact genetic testing uptake and total cost of cancer management.

Methods: We included all patients who attended the Cancer Genetics Service at the National Cancer Centre Singapore (January 2014-May 2016). Two subsidy schemes, the blanket scheme (100% subsidy to all eligible patients), and the varied scheme (patients received 50%-100% subsidy dependent on financial status) were compared. We estimated total spending on cancer management from government's perspective using a decision model.

Results: 445 patients were included. Contrasting against the blanket scheme, the varied scheme observed a higher attendance of patients (34 vs 8 patients per month), of which a higher proportion underwent genetic testing (5% vs 38%), while lowering subsidy spending per person (S$1098 vs S$1161). The varied scheme may potentially save cost by reducing unnecessary cancer surveillance when first-degree relatives uptake rate is above 36%.

Findings: Provision of subsidy leads to a considerable increase in genetic testing uptake rate. From the government's perspective, subsidising genetic testing may potentially reduce total costs on cancer management.

Keywords: Cancer genetics; Genetic screening/counselling; subsidy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cost-Benefit Analysis / economics*
  • Female
  • Genetic Testing / economics*
  • Humans
  • Male
  • Neoplasms / economics*
  • Neoplasms / epidemiology*
  • Neoplasms / genetics
  • Neoplasms / therapy
  • Pilot Projects
  • Singapore