Dynamics of Ebola RNA Persistence in Semen: A Report From the Postebogui Cohort in Guinea

Clin Infect Dis. 2017 Jun 15;64(12):1788-1790. doi: 10.1093/cid/cix210.

Abstract

This study modeled the presence of Ebola virus RNA in the semen of male Ebola survivors participating in the Postebogui study in Guinea. The median time of reverse-transcription polymerase chain reaction negativity was 46.4 days after symptom onset (95% confidence interval, 11-82.6). The results emphasize the importance of the World Health Organization recommendations for survivors' management.

Keywords: Ebola; Guinea; PCR.; semen; sexual transmission.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Cohort Studies
  • Disease Outbreaks
  • Ebolavirus / genetics
  • Ebolavirus / isolation & purification*
  • Ebolavirus / physiology
  • Guinea / epidemiology
  • Hemorrhagic Fever, Ebola / epidemiology
  • Hemorrhagic Fever, Ebola / transmission
  • Hemorrhagic Fever, Ebola / virology*
  • Humans
  • Male
  • Middle Aged
  • RNA, Viral / isolation & purification*
  • Reverse Transcriptase Polymerase Chain Reaction
  • Semen / virology*
  • Statistics, Nonparametric
  • Young Adult

Substances

  • RNA, Viral