A fatal Clostridium perfringens infection with hemolysis after chemotherapy in an adolescent

Arch Argent Pediatr. 2017 Apr 1;115(2):e92-e95. doi: 10.5546/aap.2017.eng.e92.
[Article in English, Spanish]

Abstract
in English, Spanish

Gas gangrene, clostridial myonecrosis, is one of the most serious infectious diseases, characterized by rapidly progressive destruction of deep soft tissues and production of gas within the tissues. We presented a case of fatal spontaneous gas gangrene due to Clostridium perfringens in a patient with acute lymphoblastic leukemia during remission induction chemotherapy phase.

La gangrena gaseosa, o mionecrosis clostridial, es una de las enfermedades infecciosas más graves, y se caracteriza por la rápida y progresiva destrucción de los tejidos blandos profundos y la producción de gas dentro de los tejidos. Presentamos un caso de gangrena gaseosa espontánea mortal causada por Clostridium perfringens en un paciente con leucemia linfocítica aguda durante la fase de quimioterapia de inducción de la remisión.

Keywords: child; gas gangrene; hemolysis.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anemia, Hemolytic / etiology*
  • Fatal Outcome
  • Gas Gangrene / complications*
  • Humans
  • Male
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy