Genome Sequence of Cluster W Mycobacteriophage Taptic

Catherine M Mageeney; Emily R Seier; Elise C Esposito; Lee H Graham; Emily L Heckman; Chelsea M Hipwell; Allison B Kelliher; Nicole A Lando; Patricia Y Morales; Daniel A Russell; Barbara E Tsaousis; Margaret A Kenna; Vassie C Ware

doi:10.1128/genomeA.01606-16

Genome Sequence of Cluster W Mycobacteriophage Taptic

Genome Announc. 2017 Mar 16;5(11):e01606-16. doi: 10.1128/genomeA.01606-16.

Affiliations

¹ Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA.
² Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
³ Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA vcw0@lehigh.edu.

Abstract

The Taptic genome is the first to be annotated from the W cluster of mycobacteriophages infecting Mycobacterium smegmatis mc²155. All 92 predicted open reading frames (ORFs) and a single tRNA specifying glycine (tRNA-gly) are transcribed rightward. Many functionally uncharacterized ORFs appear to be W cluster specific, as nucleotide similarity is shared only with other W cluster genomes.