Liver failure has various clinical types, a complex pathogenesis, and rapid disease progression, as well as a high mortality rate. Liver failure caused by hepatitis B virus infection is the most common type in China with severe conditions, various complications, and a mortality rate as high as 40%-90%. Invasive fungal disease secondary to acute-on-chronic liver failure can affect patients' prognosis and increase mortality rate. This article introduces the research advances in hepatitis B-related liver failure, artificial liver, and invasive fungal disease secondary to acute-on-chronic liver failure in 2016.
肝衰竭的临床类型多样、发病机制复杂，病情进展快，病死率高。我国仍以乙型肝炎病毒感染引起的肝衰竭最为常见，其他原因也逐渐增多，该病病情危重、并发症多，病死率可高达40%～90%。肝衰竭继发侵袭性真菌病将严重影响其预后，病死率增加。现对乙型肝炎相关肝衰竭、人工肝、肝衰竭继发侵袭性真菌病在2016年的研究进展进行介绍。.
Keywords: Diagnosis; Fungi; Hepatitis B virus; Infection; Liver failure; Liver, artificial; Therapeutics.