The impact of providing blood to the scene of an accident on transfusion laboratory practice

Transfus Med. 2018 Feb;28(1):56-59. doi: 10.1111/tme.12397. Epub 2017 Mar 12.

Abstract

Background: Haemorrhage is the leading cause of mortality during trauma. In 2012, London's Air Ambulance introduced Blood on Board (BOB), transfusing group O red cells (RBC) to trauma patients at the scene.

Objectives: This study assessed the impact of BOB on the number of mixed field samples received by the laboratory, the number of group O RBC transfused to non-group O patients and the ratio of RBC to fresh frozen plasma (FFP) transfused in the initial 24 h.

Methods: Three major trauma centres collected data on patients for whom the major haemorrhage protocol was activated between August 2008 and February 2012 pre-BOB and March 2012 and December 2013 post-BOB.

Results: A total of 233 trauma patients were identified pre-BOB and 119 post-BOB. There was no significant difference in the percentage of group O units transfused to non-group O patients (75 vs 82%, P = 0·21) or the RBC : FFP ratio (pre-BOB mean 1·6 [interquartile range (IQR) 1·0-2·0]; post-BOB mean 1·7 [IQR 1·1-2·2], P = 0·24). There was no significant difference in the percentage of mixed field samples received (23% vs 27%, P = 0·3).

Conclusion: The introduction of BOB did not change the proportion of group O RBC transfused or the RBC : FFP ratio; however, the proportion of acceptable samples decreased. This is largely due to an increase in blood samples not received from the post-BOB cohort, which we believe is probably due to patients who died at the scene. We have introduced robust systems to indicate reasons for not obtaining samples.

Keywords: haemorrhage; laboratory practice; pre-hospital; resuscitation; trauma.

Publication types

  • Multicenter Study

MeSH terms

  • ABO Blood-Group System*
  • Ambulances*
  • Blood Safety*
  • Erythrocyte Transfusion*
  • Female
  • Hemorrhage / therapy*
  • Humans
  • London
  • Male
  • Wounds and Injuries / therapy*

Substances

  • ABO Blood-Group System