Solvent suppression in DNP enhanced solid state NMR

J Magn Reson. 2017 Apr:277:149-153. doi: 10.1016/j.jmr.2017.02.016. Epub 2017 Mar 1.

Abstract

We show how DNP enhanced solid-state NMR spectra can be dramatically simplified by suppression of solvent signals. This is achieved by (i) exploiting the paramagnetic relaxation enhancement of solvent signals relative to materials substrates, or (ii) by using short cross-polarization contact times to transfer hyperpolarization to only directly bonded carbon-13 nuclei in frozen solutions. The methods are evaluated for organic microcrystals, surfaces and frozen solutions. We show how this allows for the acquisition of high-resolution DNP enhanced proton-proton correlation experiments to measure inter-nuclear proximities in an organic solid.

Keywords: DNP; Paramagnetic relaxation enhancement (PRE); Relaxation filters; Solid-state NMR; Solvent suppression.

Publication types

  • Research Support, Non-U.S. Gov't