Emergence of Indigenous Artemisinin-Resistant Plasmodium falciparum in Africa

N Engl J Med. 2017 Mar 9;376(10):991-3. doi: 10.1056/NEJMc1612765. Epub 2017 Feb 22.

Authors

Feng Lu¹, Richard Culleton², Meihua Zhang³, Abhinay Ramaprasad⁴, Lorenz von Seidlein⁵, Huayun Zhou¹, Guoding Zhu¹, Jianxia Tang¹, Yaobao Liu¹, Weiming Wang¹, Yuanyuan Cao¹, Sui Xu¹, Yaping Gu¹, Julin Li¹, Chao Zhang¹, Qi Gao¹, Didier Menard⁶, Arnab Pain⁴, Haitao Yang¹, Qingfeng Zhang³, Jun Cao⁷

Affiliations

¹ Jiangsu Institute of Parasitic Diseases, Wuxi, China.
² Nagasaki University, Nagasaki, Japan.
³ Shanghai East Hospital, Shanghai, China.
⁴ King Abdullah University of Science and Technology, Thuwal, Saudi Arabia.
⁵ Mahidol University, Bangkok, Thailand.
⁶ Institut Pasteur du Cambodge, Phnom Penh, Cambodia.
⁷ Jiangsu Institute of Parasitic Diseases, Wuxi, China caojuncn@hotmail.com.

PMID: 28225668
DOI: 10.1056/NEJMc1612765

No abstract available

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Africa
Antimalarials / therapeutic use*
Artemisinins / therapeutic use*
Asia, Southeastern
Drug Resistance*
Drug Therapy, Combination
Equatorial Guinea
Humans
Malaria, Falciparum / drug therapy*
Malaria, Falciparum / transmission
Male
Mutation
Papua New Guinea
Parasitemia
Plasmodium falciparum / drug effects*
Plasmodium falciparum / genetics
Plasmodium falciparum / isolation & purification
Polymorphism, Single Nucleotide
Quinolines / therapeutic use

Substances

Antimalarials
Artemisinins
Quinolines
artenimol
piperaquine