IgG4-Related Disease Causing Rapid Evolution of a Severe Aortic Valvular Stenosis

Ann Thorac Surg. 2017 Mar;103(3):e239-e240. doi: 10.1016/j.athoracsur.2016.08.045.

Abstract

Immunoglobulin G4-related systemic disease (IgG4-RSD) is a recognized emerging entity characterized by chronic fibroinflammation that can affect every organ but rarely affects the cardiovascular system. We report a rare case of IgG4-RSD involving an aortic valve that resulted in rapid progression of an aortic valvular stenosis and was successfully treated by aortic valve replacement and corticosteroids.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Aortic Valve Stenosis / etiology
  • Aortic Valve Stenosis / surgery*
  • Fibrosis
  • Heart Valve Prosthesis Implantation
  • Humans
  • Immunoglobulin G / blood*
  • Male
  • Plasma Cells / immunology

Substances

  • Immunoglobulin G