Correlation between auditory brainstem response and hearing prognosis in idiopathic sudden sensorineural hearing loss patients

Auris Nasus Larynx. 2017 Dec;44(6):678-684. doi: 10.1016/j.anl.2017.01.004. Epub 2017 Jan 31.

Abstract

Objective: To investigate the latency and amplitude of auditory brainstem response (ABR) and hearing prognosis in patients with idiopathic sudden sensorineural hearing loss (ISSNHL).

Methods: Patients with ISSNHL were classified into four different recovery groups. All patients' clinical and demographic features were analyzed. Two-channel ABRs were collected in response to click stimuli at 90dB nHL. ABR amplitudes for wave I and ABR latency for waves I, III, and V were analyzed.

Results: One hundred and two patients (54 men and 48 women) were included in the study. Hearing recovery was observed in 72 cases (70.6%). Waves I, III, and V latencies were significantly prolonged in the affected ears compared with the unaffected ears. A smaller wave I amplitude was found in the affected ear compared with the unaffected ear in the three recovery groups. There was a significant association between wave I latency and hearing outcome (p=0.009) with a prolonged trend from complete to slight hearing recovery group.

Conclusions: There was a significant correlation between wave I latency and hearing outcome in patients with ISSNHL. The finding may provide diagnostic information and serve as a potential prognostic indicator in patients with ISSNHL.

Keywords: Auditory brainstem response; Hearing outcome; Idiopathic; Sudden sensorineural hearing loss.

MeSH terms

  • Adult
  • Audiometry, Pure-Tone
  • Betamethasone / therapeutic use
  • Dextrans / therapeutic use
  • Evoked Potentials, Auditory, Brain Stem / physiology*
  • Female
  • Glucocorticoids / therapeutic use
  • Hearing Loss, Sensorineural / drug therapy
  • Hearing Loss, Sensorineural / physiopathology*
  • Hearing Loss, Sudden / drug therapy
  • Hearing Loss, Sudden / physiopathology*
  • Humans
  • Male
  • Middle Aged
  • Plasma Substitutes / therapeutic use
  • Prognosis
  • Recovery of Function*

Substances

  • Dextrans
  • Glucocorticoids
  • Plasma Substitutes
  • Betamethasone