[A Case of Small Intestinal Gastrointestinal Stromal Tumor(GIST)with Synchronous Colonic Cancer and Gastric Cancer at a Different Time]

Gan To Kagaku Ryoho. 2016 Nov;43(12):2112-2114.
[Article in Japanese]

Abstract

The patient was a 70-year-old woman with a gastrointestinalstromaltumor (GIST)of the small intestine and synchronous colonic cancer, who underwent laparoscopic right colectomy and resection of the small intestine. We started imatinib therapy because GIST belongs to a high-risk group, according to the modified Fletcher classification. Gastric cancer was diagnosed 2 years after the start of imatinib therapy. Only 4 of the 12 GIST cases seen at our institution over the last 5 years were complicated by another cancer. This is the first case of GIST in which 2 other cancers occurred at both the same and different times. We suggest that imatinib might be a factor in the development of gastric cancer.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma* / drug therapy
  • Adenocarcinoma* / surgery
  • Aged
  • Antineoplastic Agents / therapeutic use
  • Appendiceal Neoplasms / drug therapy
  • Appendiceal Neoplasms / pathology*
  • Appendiceal Neoplasms / surgery
  • Female
  • Gastrointestinal Stromal Tumors* / drug therapy
  • Gastrointestinal Stromal Tumors* / surgery
  • Humans
  • Ileal Neoplasms / drug therapy
  • Ileal Neoplasms / pathology*
  • Ileal Neoplasms / surgery
  • Imatinib Mesylate / therapeutic use
  • Neoplasms, Multiple Primary / drug therapy
  • Neoplasms, Multiple Primary / pathology*
  • Neoplasms, Multiple Primary / surgery
  • Stomach Neoplasms / drug therapy
  • Stomach Neoplasms / pathology*
  • Stomach Neoplasms / surgery
  • Treatment Outcome

Substances

  • Antineoplastic Agents
  • Imatinib Mesylate