Goats are susceptible to Bubaline alphaherpesvirus 1 infection: Results of an experimental study

Comp Immunol Microbiol Infect Dis. 2017 Feb:50:97-100. doi: 10.1016/j.cimid.2016.12.003. Epub 2016 Dec 23.

Abstract

Herpesvirus infections are generally subjected to strong host species restriction, although virological and serological investigations have revealed the possibility of cross-species infections in closely related animal species. In this study we evaluated susceptibility of goats to infection by Bubaline alphaherpesvirus 1 (BuHV-1). Four goats were inoculated intra-nasally with BuHV-1 and monitored clinically, virologically and serologically for 42days. None of the goats displayed clinical signs although all the animals variably shed the virus by the nasal route during the first 12days after infection. BuHV-1 was also detected in the white blood cells of two animals in the first week post infection. The results suggest that goats are susceptible to BuHV-1 infection and that they could play an epidemiological role in the circulation/transmission of the virus among domestic and wild ruminants and impact to some extent on the control plans for herpesviruses in cattle.

Keywords: Bubaline alphaherpesvirus 1; Epidemiology; Experimental infection; Goats; PCR; Susceptibility.

MeSH terms

  • Animals
  • Antibodies, Viral / blood
  • Asymptomatic Infections / epidemiology
  • Disease Susceptibility / veterinary
  • Female
  • Goat Diseases / epidemiology
  • Goat Diseases / transmission
  • Goat Diseases / virology*
  • Goats / virology*
  • Herpesviridae Infections / epidemiology
  • Herpesviridae Infections / transmission
  • Herpesviridae Infections / veterinary*
  • Herpesviridae Infections / virology
  • Herpesvirus 1, Bovine / immunology
  • Herpesvirus 1, Bovine / physiology*
  • Italy / epidemiology
  • Leukocytes / virology
  • Male
  • Nose / virology
  • Polymerase Chain Reaction
  • Virus Latency
  • Virus Shedding

Substances

  • Antibodies, Viral