Lighting Up ERK Activity

Dev Cell. 2017 Jan 23;40(2):115-116. doi: 10.1016/j.devcel.2016.12.016.

Abstract

Activation of extracellular signal regulated kinase (ERK) is used by many signaling pathways to control tissue patterning in a broad range of multicellular organisms. In this issue of Developmental Cell, Johnson et al. (2017) provide an optogenetic approach to manipulate this pathway with high precision and explore its signaling code.

Publication types

  • Comment

MeSH terms

  • Enzyme Activation
  • Extracellular Signal-Regulated MAP Kinases / metabolism*
  • Light*
  • MAP Kinase Signaling System
  • Optogenetics*
  • Phosphorylation
  • Signal Transduction

Substances

  • Extracellular Signal-Regulated MAP Kinases