Clinical features of hidradenitis suppurativa and Crohn disease: what do these two entities have in common?

Actas Dermosifiliogr. 2016 Sep:107 Suppl 2:21-26. doi: 10.1016/S0001-7310(17)30005-4.
[Article in English, Spanish]

Abstract

Hidradenitis suppurativa (HS) and Crohn disease (CD) are chronic, recurrent inflammatory diseases. They share certain clinical characteristics and flares are common in both. Both entities are usually diagnosed between the second and third decades of life and share risk factors such as smoking and overweight. In CD, as in HS, acute untreated episodes of inflammation can lead to sequels such as abscesses, fistulas and stenosis. Consequently, early management is of the utmost importance. Some patients have both diseases. The estimated prevalence of SH in CD patients is 12.4%-17.9%, while the prevalence of CD in HS patients is around 3%. The presence of HS in patients with inflammatory bowel disease (IBD) is associated with an earlier onset of IBD and with more frequent need for anti-TNF-alpha therapy and surgical resection.

Keywords: Asociación; Association; Crohn disease; Enfermedad de Crohn; Enfermedad inflamatoria intestinal; Evolución; Hidradenitis suppurativa; Hidradenitis supurativa; Inflammatory bowel disease; Outcome; Prevalence; Prevalencia.

Publication types

  • Review

MeSH terms

  • Abscess / etiology
  • Age of Onset
  • Colonic Neoplasms / etiology
  • Comorbidity
  • Crohn Disease / epidemiology
  • Crohn Disease / immunology
  • Crohn Disease / pathology*
  • Crohn Disease / therapy
  • Cutaneous Fistula / etiology
  • Digestive System Fistula / etiology
  • Disease Management
  • Disease Progression
  • Hidradenitis Suppurativa / epidemiology
  • Hidradenitis Suppurativa / immunology
  • Hidradenitis Suppurativa / pathology*
  • Humans
  • Intestinal Pseudo-Obstruction / etiology
  • Prevalence
  • Risk Factors