Ecthyma gangrenosum, a skin manifestation of Pseudomonas aeruginosa sepsis in a previously healthy child: A case report

Medicine (Baltimore). 2017 Jan;96(2):e5507. doi: 10.1097/MD.0000000000005507.

Abstract

Rationale: Ecthyma gangrenosum (Eg) is a necrotic lesion that is mostly seen in immunocompromised patients. It reflects a severe sepsis, possibly caused by Pseudomonas aeruginosa (Pa).

Patient concerns: A healthy 3-year-old girl admitted to the Pediatric Emergency Department presented a sepsis-associated purpura with neurological and respiratory distress.

Interventions: An empiric antibiotherapy (anti-meningococcal) was prescribed.

Diagnoses: Forty-eight hours after admission, blood and wound cultures were positive for Pa. As a result, the decision was made to change the antibiotic therapy.Unfortunately, on day 3, the patient died. Exhaustive immunologic tests are presently being carried out.

Outcomes: Eg caused by Pa is uncommon in healthy children, and purpura sepsis is usually caused by Neisseria meningitides infection.

Lessons: Eg should be recognized rapidly so that the appropriate treatment can be prescribed as quickly as possible.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Ecthyma / microbiology*
  • Fatal Outcome
  • Female
  • Humans
  • Pseudomonas Infections / complications*
  • Pseudomonas aeruginosa / isolation & purification*
  • Sepsis / microbiology*