Not Just Noise: Genomics and Genetics Bring Long Noncoding RNAs into Focus

L Stirling Churchman

doi:10.1016/j.molcel.2016.12.017

Not Just Noise: Genomics and Genetics Bring Long Noncoding RNAs into Focus

Mol Cell. 2017 Jan 5;65(1):1-2. doi: 10.1016/j.molcel.2016.12.017.

Author

L Stirling Churchman¹

Affiliation

¹ Department of Genetics, Harvard Medical School, Boston, MA 02115, USA. Electronic address: churchman@genetics.med.harvard.edu.

PMID: 28061329
DOI: 10.1016/j.molcel.2016.12.017

Abstract

Thousands of long noncoding RNAs (lncRNAs) have been annotated, yet their functions remain unclear. Recent studies-including Schlackow et al. (2017) in this issue of Molecular Cell-using orthogonal methods investigated the expression and functions of lncRNAs, resulting in deeper appreciation for the salient differences between lncRNAs and mRNAs and the roles lncRNAs serve.

MeSH terms

Genomics*
RNA, Long Noncoding*
RNA, Messenger

Substances

RNA, Long Noncoding
RNA, Messenger