Granulomatosis with polyangiitis confined to lacrimal gland, a case report

Abstract

Clinical case: A 43 year-old woman consulted due to 2 months of swelling on the superolateral side of the left orbit, with pain and erythema. An excisional biopsy was performed that revealed vasculitis with polyangiitis of the lacrimal gland. A systemic study showed that no other system was compromised.

Discussion: Orbital involvement occurs in up to 60% of patients with granulomatosis with polyangiitis. The involvement of the lacrimal gland is rare and often unilateral. Serological tests are generally negative, both in initial stages, as in localized forms of the disease.

Keywords: Anti-neutrophil cytoplasm antibody; Anticuerpo anti-citoplasma de neutrófilos; Granulomatosis con poliangeítis; Granulomatosis with polyangiitis; Necrotizing vasculitis; Vasculitis necrotizante.