Evaluation of a rapid immunochromatographic test for the detection of OXA-48 carbapenemase

Diagn Microbiol Infect Dis. 2017 Mar;87(3):266-267. doi: 10.1016/j.diagmicrobio.2016.12.001. Epub 2016 Dec 6.

Abstract

We evaluated the OXA-48K-Set, a rapid immunochromatographic test for the detection of Oxacillinase-48 (OXA-48) carbapenemases, among 37 strains expressing OXA-48 and OXA-48-like carbapenemases and 20 additional strains harboring other β-lactamases. The test showed 100% sensitivity and specificity and the results were obtained in 15minutes.

Keywords: Carbapenemase; Immunochromatography; OXA-48; Rapid detection.

Publication types

  • Evaluation Study

MeSH terms

  • Bacterial Proteins / analysis
  • Bacterial Proteins / genetics*
  • Chromatography, Affinity / methods*
  • Enterobacteriaceae / drug effects*
  • Humans
  • Microbial Sensitivity Tests
  • beta-Lactamases / analysis
  • beta-Lactamases / genetics*

Substances

  • Bacterial Proteins
  • beta-Lactamases
  • carbapenemase
  • oxacillinase