Robotic salvage retroperitoneal and pelvic lymph node dissection for 'node-only' recurrent prostate cancer: technique and initial series

BJU Int. 2017 Sep;120(3):401-408. doi: 10.1111/bju.13741. Epub 2017 Jan 14.

Abstract

Objectives: To describe the technique of robot-assisted high-extended salvage retroperitoneal and pelvic lymphadenectomy (sRPLND+PLND) for 'node-only' recurrent prostate cancer.

Patients and methods: In all, 10 patients underwent robot-assisted sRPLND+PLND (09/2015-03/2016) for 'node-only' recurrent prostate cancer, as identified by 11 C-acetate positron emission tomography/computed tomography imaging. Our anatomical template extends from bilateral renal artery/vein cranially up to Cloquet's node caudally, completely excising lymphatic-fatty tissue from aorto-caval and iliac vascular trees; RPLND precedes PLND. Meticulous node-mapping assessed nodes at four prospectively assigned anatomical zones.

Results: The median operative time was 4.8 h, estimated blood loss 100 mL and hospital stay 1 day. No patient had an intraoperative complication, open conversion or blood transfusion. Three patients had spontaneously resolving Clavien-Dindo grade II postoperative complications. The mean (range) number of nodes excised per patient was 83 (41-132) and mean (range) number of positive nodes per patient was 23 (0-109). Seven patients (70%) had positive nodes on final pathology. Node-positive rates per anatomical level I, II, III and IV were 28%, 32%, 33% and 33%, respectively. In patients with positive nodes, the median PSA level had decreased by 83% at the 2-month follow-up.

Conclusion: The initial series of robot-assisted sRPLND+PLND is presented, wherein we duplicate open surgery with superior nodal counts and decreased morbidity. Robot-assisted technical details for an anatomical LND template up to the renal vessels are presented. Longer follow-up is necessary to assess oncological outcomes.

Keywords: #PCSM; #ProstateCancer; robot-assisted surgery; salvage PLND; salvage RPLND.

MeSH terms

  • Aged
  • Humans
  • Lymph Node Excision / methods*
  • Lymph Nodes / diagnostic imaging
  • Lymph Nodes / pathology
  • Lymph Nodes / surgery*
  • Male
  • Middle Aged
  • Positron Emission Tomography Computed Tomography
  • Prostatic Neoplasms / pathology*
  • Recurrence
  • Retroperitoneal Neoplasms / diagnostic imaging
  • Retroperitoneal Neoplasms / pathology
  • Retroperitoneal Neoplasms / surgery*
  • Robotic Surgical Procedures / methods*
  • Salvage Therapy / methods*