Effects of intense pulsed light in microstomia in patients with systemic sclerosis: A pilot study

J Cosmet Laser Ther. 2017 Jun;19(3):143-148. doi: 10.1080/14764172.2016.1262961. Epub 2017 Feb 2.

Abstract

Introduction: The effects of intense pulsed light (IPL) on collagen structures are well known in the treatment of photodamaged skin.

Objective: The objective of this study was to investigate the effect of IPL on sclerotic skin by treating patients with microstomia due to systemic sclerosis.

Methods and materials: 13 patients all with microstomia and systemic sclerosis were treated with IPL, PR (530-750 nm filter) and/or VL (555-950 nm filter) applicator. They were treated in the perioral area 8 times with 3-4 weeks of interval and follow-up for 6 months. The outcomes were the inter-incisal distance and the inter-ridge distance.

Results: A significant increase in mouth opening of 4.1 mm (95% confidence interval, 1726-6638, p < 0.005) was found in the inter-ridge distance when comparing the distance before treatment with the distance at six-month follow-up. No significant difference was found in the inter-incisal distance. The patients experienced improved mobility and better control of lip movements after the treatments.

Conclusion: IPL can improve the inter-ridge distance between the lips in patients with microstomia due to systemic sclerosis but does not affect the inter-incisal distance, which is also dependent on the mobility of the mandibular joints. This treatment can be considered an adjunctive therapy in patients with microstomia due to systemic sclerosis.

Keywords: Lasers and light sources; PDT; botulinum toxins.

MeSH terms

  • Adult
  • Aged
  • Female
  • Humans
  • Intense Pulsed Light Therapy* / methods
  • Lip / physiopathology
  • Microstomia / etiology
  • Microstomia / therapy*
  • Middle Aged
  • Movement / radiation effects
  • Pilot Projects
  • Scleroderma, Systemic / complications
  • Scleroderma, Systemic / physiopathology
  • Scleroderma, Systemic / therapy*