TRPV4 Mediates Mast Cell Activation in Cathelicidin-Induced Rosacea Inflammation

J Invest Dermatol. 2017 Apr;137(4):972-975. doi: 10.1016/j.jid.2016.10.046. Epub 2016 Nov 28.

Authors

Nicholas L Mascarenhas¹, Zhenping Wang¹, Yu-Ling Chang¹, Anna Di Nardo²

Affiliations

¹ Department of Dermatology, School of Medicine, University of California, San Diego, La Jolla, California, USA.
² Department of Dermatology, School of Medicine, University of California, San Diego, La Jolla, California, USA. Electronic address: adinardo@ucsd.edu.

PMID: 27908695
DOI: 10.1016/j.jid.2016.10.046

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antimicrobial Cationic Peptides / pharmacology*
Cathelicidins / pharmacology
Inflammation / etiology*
Mast Cells / physiology*
Mice
Rosacea / etiology*
TRPV Cation Channels / physiology*

Substances

Antimicrobial Cationic Peptides
Cathelicidins
TRPV Cation Channels
Trpv4 protein, mouse

Grants and funding

R01 AI093957/AI/NIAID NIH HHS/United States