Utility of virtual touch quantification in the diagnosis of pancreatic ductal adenocarcinoma

Takumi Onoyama; Masahiko Koda; Yuki Fujise; Tomoaki Takata; Soichiro Kawata; Toshiaki Okamoto; Kennichi Miyoshi; Tomomitsu Matono; Takaaki Sugihara; Kazuya Matsumoto; Koichiro Kawaguchi; Kenichi Harada; Kazuo Yashima; Hajime Isomoto

doi:10.1016/j.clinimag.2016.11.013

Utility of virtual touch quantification in the diagnosis of pancreatic ductal adenocarcinoma

Clin Imaging. 2017 Mar-Apr:42:64-67. doi: 10.1016/j.clinimag.2016.11.013. Epub 2016 Nov 17.

Affiliations

¹ Division of Medicine and Clinical Science, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University, Yonago 683-8504, Japan.
² Division of Medicine and Clinical Science, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University, Yonago 683-8504, Japan. Electronic address: masakoda@grape.med.tottori-u.ac.jp.

PMID: 27886609
DOI: 10.1016/j.clinimag.2016.11.013

Abstract

This study aimed to compare the tissue stiffness of pancreatic ductal adenocarcinoma (PDAC) with that of pancreatic parenchyma using virtual touch quantification (VTQ). SWV was measured in 34 PDAC lesions and in pancreatic parenchyma of both controls and patients. SWVs in PDAC lesions were significantly higher than in pancreatic parenchyma in both healthy controls and in patients with PDAC. The area under the ROC for diagnosis of PDAC was 0.94 for pancreatic parenchyma in healthy controls, and 0.85 for pancreatic parenchyma in patients with PDAC. VTQ can provide a useful and additional information for diagnosis of PDAC.

Keywords: Acoustic radiation force impulse elastography; Pancreatic ductal adenocarcinoma; Shear wave velocity; Virtual touch quantification.

MeSH terms

Adult
Aged
Aged, 80 and over
Carcinoma, Pancreatic Ductal / diagnostic imaging*
Elasticity Imaging Techniques / methods*
Female
Humans
Male
Middle Aged
Pancreas / diagnostic imaging*
Pancreatic Neoplasms / diagnostic imaging*
Touch