Fine-needle cytology in the follow-up of breast carcinoma

Aging Clin Exp Res. 2017 Feb;29(Suppl 1):167-171. doi: 10.1007/s40520-016-0645-z. Epub 2016 Nov 21.

Abstract

The postoperative follow-up strategies for breast carcinoma (BC) utilize different procedures; the aim of this study was to investigate the role of fine-needle cytology (FNC) in the follow-up of BC patients. Two hundred sixty-six FNC samples from 190 BC patients have been reviewed. The target anatomical sites were 190 breast including 155 ipsilateral and 145 contralateral breast lesions and 76 extra-mammary nodules. Extra-mammary lesions included lymph nodes, thyroidal nodules, soft tissue lesions, (subcutaneous and sub-scars), salivary glands and deep located masses. Diagnostic distribution of the breast lesions was as follows: 51 positive, 15 indeterminate/suspicious, 119 negative and 5 inadequate. Positive cases included 43 ipsilateral and 8 contralateral BC, 9 BC in different quadrants from those of onset of the first BC. Sensitivity, specificity and accuracy have been 90, 91 and 90&, respectively. FNC, in a correct setting, is a reliable and effective method for the follow-up management of BC patients.

Keywords: Breast carcinoma; Fine-needle cytology; Follow-up.

MeSH terms

  • Aged
  • Biopsy, Fine-Needle / methods*
  • Breast Neoplasms* / pathology
  • Breast Neoplasms* / surgery
  • Cytodiagnosis / methods
  • Female
  • Follow-Up Studies
  • Humans
  • Italy
  • Male
  • Mastectomy / adverse effects*
  • Mastectomy / methods
  • Middle Aged
  • Neoplasm Metastasis / pathology*
  • Neoplasm Recurrence, Local / pathology*
  • Postoperative Period
  • Reproducibility of Results
  • Sensitivity and Specificity