The Dual Role of EPOP and Elongin BC in Controlling Transcriptional Activity

Karin Johanna Ferrari; Elisa Lavarone; Diego Pasini

doi:10.1016/j.molcel.2016.11.009

The Dual Role of EPOP and Elongin BC in Controlling Transcriptional Activity

Mol Cell. 2016 Nov 17;64(4):637-638. doi: 10.1016/j.molcel.2016.11.009.

Authors

Karin Johanna Ferrari¹, Elisa Lavarone¹, Diego Pasini²

Affiliations

¹ Department of Experimental Oncology, European Institute of Oncology, Via Adamello 16, 20139 Milan, Italy.
² Department of Experimental Oncology, European Institute of Oncology, Via Adamello 16, 20139 Milan, Italy. Electronic address: diego.pasini@ieo.eu.

PMID: 27863221
DOI: 10.1016/j.molcel.2016.11.009

Abstract

Two studies published in this issue of Molecular Cell (Beringer et al., 2016; Liefke et al., 2016) characterize the novel interaction of EPOP with Elongin BC in regulating gene transcription at both H3K4me3-broad active and H3K27me3 Polycomb-repressed chromatin domains.

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