Abstract
An efficient (+)-camphor-mediated kinetic resolution of racemic cyclohex-2-en-1-ylalane is described. This approach provides an enantiomerically enriched form of the alane, in situ available for synthetic uses. Applied to the allylation of aldehydes, this protocol leads to the corresponding homoallylalcohols in a highly enantioselective manner.
MeSH terms
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Camphor / chemistry*
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Cyclohexanes / chemistry*
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Cyclohexanes / isolation & purification*
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Cyclohexenes / chemistry*
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Cyclohexenes / isolation & purification*
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Kinetics
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Models, Molecular
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Molecular Conformation
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Organometallic Compounds / chemistry*
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Organometallic Compounds / isolation & purification*
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Stereoisomerism
Substances
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Cyclohexanes
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Cyclohexenes
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Organometallic Compounds
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Camphor