Silence without stress

David J Young; Nicholas R Guydosh

doi:10.7554/eLife.22073

Silence without stress

Elife. 2016 Nov 11:5:e22073. doi: 10.7554/eLife.22073.

Authors

David J Young¹, Nicholas R Guydosh¹

Affiliation

¹ Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, United States.

Abstract

Two mechanisms ensure that the mRNA encoding Hac1 protein, a transcription factor involved in the unfolded protein response, is only translated when it is needed.

Keywords: S. cerevisiae; chromosomes; genes; translation; ubiquitination; unfolded protein response.

Publication types

Comment

MeSH terms

Basic-Leucine Zipper Transcription Factors / genetics
RNA, Messenger
Repressor Proteins / genetics
Saccharomyces cerevisiae / genetics
Saccharomyces cerevisiae Proteins / genetics*
Unfolded Protein Response

Substances

Basic-Leucine Zipper Transcription Factors
HAC1 protein, S cerevisiae
RNA, Messenger
Repressor Proteins
Saccharomyces cerevisiae Proteins