Polarized monolayer cultures of human intestinal epithelial cell lines exposed to intractable proteins - In vitro hazard identification studies

Food Chem Toxicol. 2016 Dec;98(Pt B):262-268. doi: 10.1016/j.fct.2016.11.006. Epub 2016 Nov 8.

Authors

Bryan P Hurley¹, Alex D Eaton², Cindi Zimmermann³, Bryan Delaney³

Affiliations

¹ Mucosal Immunology & Biology Research Center, Massachusetts General Hospital, 55 Fruit Street, Jackson 1402, Boston, MA, 02114, USA; Department of Pediatrics, Harvard Medical School, Boston, MA, USA. Electronic address: bphurley@partners.org.
² Mucosal Immunology & Biology Research Center, Massachusetts General Hospital, 55 Fruit Street, Jackson 1402, Boston, MA, 02114, USA.
³ DuPont Pioneer, 8325 NW 62ndAvenue, Johnston, IA, 50131, USA.

PMID: 27832974
DOI: 10.1016/j.fct.2016.11.006

No abstract available

Keywords: Cytotoxicity; Intestinal epithelial cells; Intractable proteins.

MeSH terms

Activating Transcription Factor 2 / toxicity*
Bacteriorhodopsins / toxicity*
Cell Culture Techniques / methods*
Epithelial Cells / drug effects*
Follistatin / toxicity*
Humans
In Vitro Techniques
Intestines / drug effects*
Proto-Oncogene Proteins c-met / toxicity*
Toxicity Tests

Substances

Activating Transcription Factor 2
Follistatin
Bacteriorhodopsins
Proto-Oncogene Proteins c-met