Abstract
The Mitotic Exit Network (MEN) is an essential signaling pathway, closely related to the Hippo pathway in mammals, which promotes mitotic exit and initiates cytokinesis in the budding yeast Saccharomyces cerevisiae. Here, we summarize the current knowledge about the MEN components and their regulation.
Keywords:
Cdc14 phosphatase; Hippo pathway; MEN; Mitosis; Mitotic exit network.
MeSH terms
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Cell Cycle
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Cell Cycle Proteins / metabolism*
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Cytokinesis
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Mitosis
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Protein Tyrosine Phosphatases / metabolism*
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Saccharomyces cerevisiae / cytology*
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Saccharomyces cerevisiae / metabolism
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Saccharomyces cerevisiae Proteins / metabolism*
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Signal Transduction*
Substances
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CDC14 protein, S cerevisiae
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Cell Cycle Proteins
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Saccharomyces cerevisiae Proteins
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Protein Tyrosine Phosphatases