Unwinding Limb Development

Diego Villar; Duncan T Odom

doi:10.1016/j.cell.2016.10.007

Unwinding Limb Development

Cell. 2016 Oct 20;167(3):598-600. doi: 10.1016/j.cell.2016.10.007.

Authors

Diego Villar¹, Duncan T Odom²

Affiliations

¹ University of Cambridge, Cancer Research UK Cambridge Institute, Robinson Way, Cambridge CB2 0RE, UK.
² University of Cambridge, Cancer Research UK Cambridge Institute, Robinson Way, Cambridge CB2 0RE, UK. Electronic address: duncan.odom@cruk.cam.ac.uk.

PMID: 27768881
DOI: 10.1016/j.cell.2016.10.007

Abstract

The molecular mechanisms underpinning vertebrate body plan evolution are beginning to be unravelled. In this issue of Cell, Kvon et al. spectacularly demonstrate how transplanting snake-specific genetic changes found uniquely in serpent enhancers leads to limb loss in mice.

Publication types

Comment

MeSH terms

Animals
Biological Evolution
Extremities*
Vertebrates*

Grants and funding

20412/CRUK_/Cancer Research UK/United Kingdom