The prevalence and genotype distribution of rotavirus A infection among children with acute gastroenteritis in Kunming, China

Arch Virol. 2017 Jan;162(1):281-285. doi: 10.1007/s00705-016-3102-6. Epub 2016 Oct 7.

Abstract

The aim of this study was to determine the prevalence of rotavirus A (RVA) infections in children from Kunming, China, and the RVA genotypes present. A total of 16,311 children with acute gastroenteritis were recruited for the study, and 33.1 % (5,394/16,311) were RVA positive. Children under 24 months of age were more susceptible to RVA infection, with an infection rate of 87.4 % (4,712/5,394). The most prevalent genotype was G9P[8] (85/107, 79.4 %), which showed high sequence similarity to G9P[8] strains from other regions of China and neighbouring countries, but not to the licensed vaccine strain LLR. These findings should be useful for the prevention of RVA infections.

Keywords: Children; Epidemiology; Gastroenteritis; Genotype; Rotavirus A.

MeSH terms

  • Adolescent
  • Age Factors
  • Child
  • Child, Preschool
  • China / epidemiology
  • Female
  • Gastroenteritis / epidemiology*
  • Gastroenteritis / virology
  • Genotype*
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Molecular Epidemiology
  • Prevalence
  • Rotavirus / classification*
  • Rotavirus / genetics*
  • Rotavirus / isolation & purification
  • Rotavirus Infections / epidemiology*
  • Rotavirus Infections / virology