A Rare Case of S310F Somatic ERBB2 Mutation in a HER2-Nonamplified Breast Cancer

Clin Breast Cancer. 2017 Feb;17(1):e37-e41. doi: 10.1016/j.clbc.2016.08.001. Epub 2016 Aug 18.
No abstract available

Keywords: Immunohistochemistry; Neratinib; Personalized medicine; Pertuzumab; Trastuzumab.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Animals
  • Antineoplastic Agents, Immunological / pharmacology
  • Antineoplastic Agents, Immunological / therapeutic use*
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Bone Neoplasms / diagnostic imaging
  • Bone Neoplasms / genetics*
  • Bone Neoplasms / secondary
  • Bone Neoplasms / therapy
  • Breast / diagnostic imaging
  • Breast / pathology
  • Breast / surgery
  • Breast Neoplasms / diagnostic imaging
  • Breast Neoplasms / genetics*
  • Breast Neoplasms / pathology
  • Breast Neoplasms / therapy
  • Carcinoma, Ductal, Breast / diagnostic imaging
  • Carcinoma, Ductal, Breast / genetics*
  • Carcinoma, Ductal, Breast / secondary
  • Carcinoma, Ductal, Breast / therapy
  • Carcinoma, Intraductal, Noninfiltrating / diagnostic imaging
  • Carcinoma, Intraductal, Noninfiltrating / genetics*
  • Carcinoma, Intraductal, Noninfiltrating / pathology
  • Carcinoma, Intraductal, Noninfiltrating / therapy
  • Chemotherapy, Adjuvant / methods
  • Drug Resistance, Neoplasm / genetics
  • Female
  • High-Throughput Nucleotide Sequencing
  • Humans
  • Liver Neoplasms / diagnostic imaging
  • Liver Neoplasms / genetics*
  • Liver Neoplasms / secondary
  • Liver Neoplasms / therapy
  • Mammography
  • Mastectomy, Segmental
  • Mutation
  • Positron Emission Tomography Computed Tomography
  • Radiotherapy, Adjuvant
  • Receptor, ErbB-2 / genetics*
  • Sentinel Lymph Node Biopsy
  • Trastuzumab / pharmacology
  • Trastuzumab / therapeutic use*
  • Treatment Outcome

Substances

  • Antineoplastic Agents, Immunological
  • ERBB2 protein, human
  • Receptor, ErbB-2
  • Trastuzumab