Herpes Zoster Ophthalmicus: A Review for the Internist

Am J Med. 2017 Jan;130(1):21-26. doi: 10.1016/j.amjmed.2016.08.039. Epub 2016 Sep 17.

Abstract

Herpes zoster ophthalmicus occurs due to reactivation of the varicella zoster virus in the ophthalmic branch of the fifth cranial nerve. This disease primarily affects the elderly as well as the immunocompromised and can result in a wide range of ophthalmic morbidity. Systemic antiviral therapy is the mainstay of treatment; however, consultation with an ophthalmologist is typically indicated. Herein we present a review of this common entity including epidemiology, pathophysiology, evaluation, treatment, follow-up, and an update on the current body of literature.

Keywords: Herpes zoster ophthalmicus; Hutchinson sign; Shingles.

Publication types

  • Review

MeSH terms

  • Antiviral Agents / therapeutic use
  • Diagnosis, Differential
  • Eye / pathology
  • Herpes Zoster Ophthalmicus / diagnosis
  • Herpes Zoster Ophthalmicus / drug therapy*
  • Herpes Zoster Ophthalmicus / etiology
  • Herpes Zoster Ophthalmicus / prevention & control
  • Humans
  • Internal Medicine / methods

Substances

  • Antiviral Agents