Decoding the Protein Destruction Code: A Panoramic View

Mol Cell. 2016 Sep 15;63(6):915-7. doi: 10.1016/j.molcel.2016.08.028.

Abstract

Proteasome degradation is essential, but the intrinsic features of a protein that signals its destruction remain incompletely understood. In this issue of Molecular Cell, Geffen et al. (2016) report an unbiased and proteome-wide method that provided insights into the protein destruction signals and pathways.

Publication types

  • Comment

MeSH terms

  • Proteasome Endopeptidase Complex*
  • Proteome*

Substances

  • Proteome
  • Proteasome Endopeptidase Complex